Has anesthetic effects at high concentrations in animal studies; [ChemIDplus] Included in list of "fragrance substances with negative human data, i.e. Toxic effects. Flash Point(F) 230.0 °F - closed cup. It started from d -glucose, which was converted into the orthogonally protected D-glucitol having the trityl block at the C-6 position and the silyl block at the C1-position. Chemical Database - Benzyl Acetate. May cause long-term adverse effects in the environment. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. It's the esterification of salicylic acid with benzyl alcohol. This method employs the acid-catalyzed reaction of benzyl alcohol with acetic acid to produce benzyl acetate responsible for the characteristic odor of peaches. PubMed:Effects of corn oil and benzyl acetate on number and size of azaserine-induced foci in . EnvironmentalChemistry.com. Regulatory process names 2 CAS names 1 IUPAC names 16 Trade names 1 Other identifiers 1 . Benzyl benzoate is an acaricide that is used in the treatment of scabies. The reactions are sensitive to steric effects . Registry of Toxic Effects of Chemical Substances (RTECS) Licensing Agreement Signed for RTECS ; is polar because of the bent shape of the molecule. In particular, linalool and linalyl acetate, the two main components of lavender oil, can be cytotoxic: in a concentration of .25%, these components cause cell death. In addition to the 19 constituents FDA proposes to add to the list of Harmful and Potentially Harmful Constituents, FDA should also add compounds that may be . It is also used as an excipient in some testosterone -replacement medications (like Nebido) for treating hypogonadism. Harmful to aquatic life with long lasting effects. Though jasmine oil is extracted mainly from Jasmine flower, its chemical composition includes a variety of constituents that includes phytol, benzyl benzoate, benzyl alcohol, benzyl acetate, nerolidol, benzoic acid, farnesol and a lot of other ingredients. H401 : Toxic to aquatic life. Precautionary Statement: . Blister formation, crusting, itching, oozing, reddening, or scaling of skin. . Benzyl acetate also occurs naturally in a variety of fruits and flowers. Inspired! No effects detected at 30% RH to 92% RH. Ann Pharmacother. Physical Properties . FIRST-AID MEASURES. Harmful to aquatic life with long lasting effects. The UV spectrum of benzyl acetate in methanol indicates no absorption above 290 nm, suggesting this compound is not expected to directly photolyze(3). Chronic risk. Accessed on-line: 5/8/2022 . glycine-supplemented diets had an increased rate . PMID: 6847756; PMCID: PMC1874682 Free PMC article. Flash Point(C) > 110 °C - closed cup. (.25% is a fairly . Individual Animal Data. Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the Benzyl acetate is a compound that has a sweet aroma, similar to jasmine. Benzyl acetate is a flavouring agent Benzyl acetate is an organic . H412 : Harmful to aquatic life with long lasting effects. It's used a ton in making perfume and cosmetics for its aroma and in flavorings to impart apple and pear flavors. 4.2.2. 1994 Jan;28(1):59-60. Weakness. The substance may have effects on the kidneys. Benzyl acetate. These side effects may go away during treatment as your body adjusts to the medicine. another important acetate compound, benzyl acetate, is still manufactured by the harmful chlorination of toluene and subsequent conversion of benzyl chloride and alkali acetate. For Healthcare Professionals. Whereas synthetic benzyl acetate is all about jasmine, this completely natural isolate is all about ylang ylang in perfect harmony with jasmine. Exposure to 5 mg/fi. . 20,000 ppm benzyl acetate (BA), and 90% of rats re- ceiving 35,000 ppm BA or 50,000 pprn BA with glycine survived until the end of the study. It is released during the production of artificial silk and leather, and during the preparation of photographic films and plates. Esters react with acids to liberate heat along with alcohols and acids. (BENZYL ACETATE) Transport Hazard Class(es) 9 : Subsidiary Class(es) - Packing Group: III : Environmental Hazards: Marine Pollutant: Yes : The synthesis of the precursors of 7-membered iminosugars: 26, 28, 30, and 31, was described. Jasmine oil is non-toxic which is why it is preferred widely. Removal of the trityl group from C6 and installing the oxime function there . PMID: 6847756; PMCID: PMC1874682 Free PMC article. ThOD 2.50 g O₂/g substance 12.3. Benzene-based ingredients are often . Effects of short-term exposure . Some side effects of benzyl benzoate topical may occur that usually do not need medical attention. Acceptable daily intakes were established by the World Health Organization at 5 mg/kg for Benzyl . Benzyl Acetate Section 1: Chemical Product and Company Identification Product Name : BENZYL ACETATE CAS# : 140-11-4 . Per the Laundry Investigation we shared that according to its own material safety sheet, benzyl acetate is toxic if inhaled or ingested. MSDS Sheet, MATERIAL SAFETY DATA SHEET . May . Benzyl acetate is also used as a solvent in plastics and resin, cellulose acetate, nitrate, oils, lacquers, polishes and inks. Esters react with acids to liberate heat along with alcohols and acids. It is a colorless liquid with a mild, sweet, floral smell. The effect of benzyl alcohol, benzyl acetate and benzyl benzoate when given by mouth upon the blood pressure, pulse and . Benzyl acetate Revision Date 14-Feb-2020 Prepared By Health, Safety and Environmental Department Email: tech@alfa.com www.alfa.com Revision Date 14-Feb-2020 Print Date 14-Feb-2020 Revision Summary SDS authoring systems update, replaces ChemGes SDS No. Epidural administration of methylprednisolone acetate preserved with benzyl alcohol. The rate constant . King CC, Hart LL. Benzyl salicylate is one of the first skincare ingredients to help protect the skin from UV rates. Special Remarks on Toxicity to Animals: Not available. Inhalation risk A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. Information on toxicological effects Acute toxicity May be harmful if swallowed. Benzyl Alcohol is metabolized to Benzoic Acid, which reacts with glycine and excreted as hippuric acid in the human body. All Photos (1) Empirical Formula (Hill Notation): C 10 H 9 NO 2. Inhaling benzyl alcohol in sufficient quantities may cause nervous system depression with symptoms of nausea, lightheadedness, drowsiness, dizziness and lack of coordination. WGK 2. . 140-11-4. General-The most frequently reported adverse reactions (incidence 6% or greater) are vomiting, hyperglycemia, hypokalemia, convulsions, and mental impairment.-Patients 30 days of age or younger had more blood and lymphatic system disorders and vascular disorders (specifically hypotension . Ann Pharmacother. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. another important acetate compound, benzyl acetate, is still manufactured by the harmful chlorination of toluene and subsequent conversion of benzyl chloride and alkali acetate. Midterm assignment chan lab report for lab esterification of acetic acid with benzyl alcohol to produce benzyl acetate ivan chan abstract benzyl acetate was. Benzyl Acetate is an ester of benzyl alcohol and acetic acid. 1994. Even back in the 1920s! 1994. Product Species Test Results BENZYL ACETATE (CAS 140-11-4) LD50 Rabbit Dermal Acute > 5000 mg/kg - AvoBath Contains: Citral. Food Chem Toxicol. Le Chatelier's principle regarding the effects of reactant concentration and temperature were also employed to increase the percentage ester yield. . Benzyl Acetate. It is also toxic to mite ova, though its exact mechanism of action is unknown. 97%. 5  The reason tocopheryl acetate may increase the risk of a stroke is due to its anti-blood-clotting side effects. Diamond Hazard Value Description; 2 1 0 Health 1: . Information on toxicological effects Acute toxicity May be harmful if swallowed. PRODUCT AND COMPANY IDENTIFICATION. P273 : Avoid release to the environment. Item in Clipboard Toxic Effects of Benzyl Alcohol . Harmful if inhaled. 1986; 68:197-201. Product Species Test Results BENZYL ACETATE (CAS 140-11-4) LD50 Rabbit Dermal Acute > 5000 mg/kg Pathology Tables, Survival and Growth Curves. the toxic effects of benzyl acetate. 3. Rash. Ann Pharmacother. Benzyl acetate Benzyl acetate (ACGIH) Benzyl ethanoate Benzylester kyseliny octove (Czech) NCI-C06508 . . Benzyl acetate is also used for industrial uses, especially as a solvent in plastics and resins, nitrates, oils and lacquers. Benzyl acetate was reported to give negative results in the Bacillus subtilis rec assay. BENZYL ACETATE is an ester. Decreases viscosity: Benzyl alcohol also decreases viscosity, which allows products to flow more easily. Potential side effects of toxic fragrance chemicals. sur- vival, food intake, and body weight and showed no ab- . Acetaldehyde is a human carcinogen (3) and studies show it can cross the placenta to a fetus. (Benzyl Acetate) DATE PREPARED: 5/11/2016 Page 1 of 7 Section 1. Experimental systems . Herrington and Myers (2015) have detected approximately 60 . 1995 Feb;33(2):151-8.Pubmed Abstract; Male Rats: F344/N; Male Mice: B6C3F1 goldfish, Carasslus auratas. 12.2. An FDA analysis (1968-1972) of 138 compounds used in cosmetics that most frequently involved adverse reactions, identified five chemicals (alpha-terpineol, benzyl acetate, benzyl alcohol, limonene and linalool) that are among the 20 most commonly used in the 31 fragrance products tested by the EPA in 1991! NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: AF5075000; 1738; Last Updated Date : 12/17/2020 ×. P270 : Do not eat, drink or smoke when using this product. Benzyl benzoate exerts toxic effects on the nervous system of the parasite, resulting in its death. each person who uses a toxic gas as a regular part of their job must have their exposure monitored periodically. A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. Benzyl salicylate is one of the first skincare ingredients to help protect the skin from UV rates. benzyl ethanoate; acetic acid benzyl ester; phenylmethyl acetate; α-acetoxytoluene; phenylmethyl ethanoate. H412 Harmful to aquatic life with long lasting effects. WGK 2. Even back in the 1920s! Synonyms. Evaluation of the Chronic Toxicity and Carcinogenicity (C06508B) of Benzyl Acetate (140-11-4) in F344/N Rats Exposed via Dosed Feed. Benzyl acetate occurs in jasmine, apple, cherry, guava fruit and peel, wine grape, white wine, tea, plum, cooked rice, Bourbon vanilla, naranjila fruit (Solanum quitoense), Chinese cabbage and quince. Add to cart. be evident in a fragrance, and thus, it is relatively safe to use; it is extremely difficult for anyone to suffer from negative side effects, such as toxicity, from benzyl . is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring . Lavender won't likely sensitize skin in a noticeable way-the way that a chemical peel might-but repeated use of lavender oil may damage skin over time. patch tests of patients with suspected contact allergy to fragrance ingredients which yielded . The . It's also irritating to the eyes, lungs, and skin. Aconitine is also present in Yunnan Baiyao, a proprietary traditional Chinese medicine. Therefore, benzyl acetate is not expected to pose an acute risk. Effects of Air Pollution on your health; Clean Air Act Contributing to Mercury Problem; Nitrogen Dioxide, Ozone & Lead Partner to Increase Pollution Dangers to Urban Children . The substance may have effects on the kidneys. BENZYL ACETATE: ICSC: 1331 (March 1999) Phenylmethyl acetate Acetic acid, benzyl ester: . Product Name & Other Names: Benzyl Acetate or Acetic Acid Benzyl Ester. King CC, et al. . Department of Labor logo . Identification; Type of substance; Substance identifiers; Compositions; Identification. Effects of long-term or repeated exposure The substance defats the skin, which may cause dryness or cracking. F344 . Contact sensitivity to fragrance mix is not infrequent . Pathology Tables. It is released during the manufacture of linoleum, Benzyl benzoate is used as a topical . 4.2.1. The blogs listed the following ingredients as toxic components of dryer sheets: Alpha-Terpineol, Benzyl acetate, Benzyl alcohol, Chloroform, Ethanol, Ethyl Acetate, Linalool, and Pentane. . Short-Term Health Effects Benzyl acetate may be irritating to skin and eyes. wintergreen oil is some 1.5-4.5 times more toxic to humans . Precautionary Statements: P501 : Dispose of contents/ container to an approved waste disposal plant. Benzyl benzoate is an effective and inexpensive topical treatment for human scabies. R51/53 = Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Toulene or methyl benzene present in most . Sodium Benzoate is the sodium salt of Benzoic Acid used as a preservative, also in a wide range of cosmetic product types. lowest published toxic dose: 258 gm/kg/2Y- intermittent: Tumorigenic: Neoplastic by RTECS criteria . We were . CLP INFORMATION Amber and Sweet Orange Contains EUGENOL, LIMONENE, LINALOOL, LINALYL ACETATE, TETRAMETHYL ACETYLOCTAHYDRONAPHTHALENES.May produce an allergic reaction. Ecology - water : No data available on ecotoxicity. Accuracy Effects of long-term or repeated exposure The substance defats the skin, which may cause dryness or cracking. Health Perspect. BENZYL ACETATE SDS, SAFETY DATA SHEET. [Use of orthogonal plans for the experimental analysis of the combined effects of harmful substances]. In general, e-cigarettes often contain ingredients such as propylene glycol (PG) and glycerol, mixed with concentrated flavors and, optionally, a variable percentage of nicotine. P270 : Do not eat, drink or smoke when using this product. Of these effects, 62.8% would be considered disabling under the definition of the Americans with Disabilities Act. Flash Point(F) 230.0 °F - closed cup. Product and Company Identification Product Name Benzyl Acetate CAS Number 140-11-4 Parchem - fine & specialty chemicals 415 Huguenot Street New Rochelle, NY 10801 (914) 654-6800 (914) 654-6899 parchem.com info@parchem.com EMERGENCY RESPONSE NUMBER CHEMTEL It is a colorless liquid with a mild, sweet, floral smell. 97%. WGK. Heat is also generated by the interaction of esters with caustic solutions. H401 : Toxic to aquatic life.

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